細(xì)胞代謝

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal  AMPK

醛縮酶抑制劑aldometanib模擬葡萄糖饑餓激活溶酶體AMPK

廈門大學(xué)

Nature Metabolism

20.8

Click-Chemistry-Enabled Nanopipettes for the Capture and Dynamic Analysis of a Single Mitochondrion inside One Living Cell

點(diǎn)擊化學(xué)實(shí)現(xiàn)納米管捕獲和動(dòng)態(tài)分析單個(gè)線粒體

南京大學(xué)

Angewandte Chemie International Edition

Fluorescent Polymerase Chain Reaction Nanokit for the Detection of DNA Sequence in Single Living Cells

PCR反應(yīng)納米試劑盒檢測單個(gè)活細(xì)胞DNA序列

南京大學(xué)

Analytical Chemistry

Pharmaceutical Manipulation of Mitochondrial F0F1-ATP Synthase Enables Imaging and Protection of Myocardial Ischemia/Reperfusion Injury Through Stress-induced Selective Enrichment

靶向調(diào)控線粒體ATP合酶小分子化合物研發(fā)

陸軍軍醫(yī)大學(xué)

Advanced Science

In Situ Measurement of ATP in Single Cells by an Amphiphilic Aptamer-Assisted Electrochemical Nano-Biosensor

雙親性適配體電化學(xué)納米生物傳感器實(shí)現(xiàn)單細(xì)胞ATP的原位檢測

湖北大學(xué)

Analytical Chemistry

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery

內(nèi)質(zhì)網(wǎng)膜輔助脂質(zhì)體給藥突破免疫原性化療的時(shí)空屏障

ACS Nano

用于監(jiān)測細(xì)胞凋亡過程中亞細(xì)胞室中細(xì)胞色素C的光學(xué)和電化學(xué)探針

中國地質(zhì)大學(xué)

Angewandte Chemie International Edition

Overcoming the On-Target Toxicity in Antibody-Mediated Therapies via an Indirect Active Targeting Strategy

“INTACT”策略克服抗體介導(dǎo)療法中的靶向毒性

西南大學(xué)

Advanced Science

Probing the interaction between metastatic breast cancer cells and osteoblasts in a thread-based breast–bone co-culture device

探討轉(zhuǎn)移性乳腺癌細(xì)胞與成骨細(xì)胞在線狀胸骨共培養(yǎng)裝置中的相互作用

西南大學(xué)

Lab on a Chip

Spatial Analysis of Reactive Oxygen Species in a 3D Cell Model Using a Sensitive Nanocavity Electrode

利用敏感納米空腔電極對三維細(xì)胞模型中的活性氧進(jìn)行空間分析

南京大學(xué)

ACS Applied Materials& Interface

Endogenous Protease-Activatable Nanosensor Based on PNA–Peptide–DNA Engineering for AND-Gated and Dual-Model Detection of MicroRNA in Single Living Tumor Cells 

單個(gè)活腫瘤細(xì)胞MicroRNA的檢測

湖北大學(xué)

ACS Applied Materials& Interface

Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine derived ionizable-lipidoid nanoparticles

構(gòu)建主動(dòng)分布新策略并揭示天然產(chǎn)物輔助藥物遞送潛力

西南大學(xué)

Nature Communications

The influence of spheroid maturity on fusion dynamics and micro-tissue assembly in 3D tumor models

球體成熟度在三維腫瘤模型中對融合動(dòng)力學(xué)和微組織組裝的影響

西南大學(xué)

Biofabrication

An Integrated Modular Vaccination System for Spatiotemporally Separated Perioperative Cancer Immunotherapy

一種用于時(shí)空分離的圍手術(shù)期癌癥免疫治療的集成模塊化疫苗接種系統(tǒng)研發(fā)

西南大學(xué)

Advanced Materials

Dynamics of estrogen-induced ROS and DNA strand break generation in estrogen receptor a-positive breast cancer

雌激素受體a陽性乳腺癌中雌激素誘導(dǎo)活性氧和DNA鏈斷裂的動(dòng)態(tài)變化

中國藥科大學(xué)

Biochemical and Biophysical Research Communications

Molecularly assembled graphdiyne with atomic sites for ultrafast and real-time detection of nitric oxide in cell assays

具有原子位點(diǎn)的分子組裝石墨烯用于細(xì)胞中一氧化氮的超快速實(shí)時(shí)檢測

蘇州科技大學(xué)

Biosensors and Bioelectronics 

Development of Dual-Nanopore Biosensors for Detection of Intracellular Dopamine and Dopamine Efflux from Single PC12 Cell

雙納米孔生物傳感器用于單個(gè)PC2細(xì)胞內(nèi)外多巴胺檢測

湖南大學(xué)

Analytical Chemistry

A new method for evaluating the quality of single sperm by detecting reactive oxygen  species

一種通過檢測活性氧來評估單精子質(zhì)量的新方法

華中科技大學(xué)

Chinese Chemical Letters

Metabolic profling identifes Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse sperm

線粒體功能評估

四川大學(xué)華西二院

Cellular and Molecular Life Sciences

Progressive polyadenylation and m6A modifcation of Ighg1 mRNA maintain IgG1 antibody homeostasis in antibody-secreting cells

細(xì)胞核提取

清華大學(xué)

Immunity